Regarding objective assessment of endo-periodontal pathologies prevalence

Authors

DOI:

https://doi.org/10.32782/2415-8127.2026.73.14

Keywords:

endodontics, periodontology, endo-periodontal lesions, tooth, pulp, periodontium, periodontitis, prevalence, diagnostics, diagnostic criteria

Abstract

In the context of studying prevalence and treatment characteristics of endo-periodontal lesions across different patient cohorts, as well as evaluating the feasibility of modifying existing diagnostic and prognostic algorithms in light of ongoing digitalization in dental practice, it is essential to objectively determine the frequency of these conditions based on available evidences and to assess the applicability and validity of the clinical and radiological criteria used for their identification.
Objective – to analyze and objectively assess prevalence rates of endo-periodontal lesions at different levels of analysis reported in previous studies, and to evaluate the association of these rates with other patient-related factors.
Study was designed as a targeted literature review with elements of comparative data synthesis regarding the prevalence of endo-periodontal lesions and factors associated with their diagnostic frequency. Included studies met the following criteria if: 1) reported prevalence rates of endo-periodontal lesions at the level of patient cohorts and/or analyzed teeth; 2) applied defined diagnostic criteria (clinical and/or radiological) and/or classification systems; 3) provided data on associations between prevalence rates and other factors (age, sex, periodontal status, systemic conditions, or localization).
Analyzed studies demonstrated that endo-periodontal lesions exhibit a heterogeneous epidemiological profile, which varies substantially depending on sample characteristics and diagnostic approach employed. Across different cohorts pathology shows an association with age, with tendency toward higher prevalence among older patients at the patient-oriented level. However, at the tooth level, alternative prevalence peaks may be observed, reflecting the influence of sample structure and methodological approaches. Several studies report a predominance of more advanced lesion stages (grades II-III), potentially reflecting a «clinical selection» effect favoring patients with more pronounced symptoms.
Prevalence of endo-periodontal lesions is characterized by marked variability: according to clinical observations it ranges 0,4-5,0%, whereas in specific patient cohorts and radiological studies it reaches 14-31%. These discrepancies are attributable to differences in study design, levels of analysis (patient-based versus tooth-based), applied classifications, and diagnostic criteria. Most studies identify associations between prevalence and age, presence and severity of periodontitis, systemic conditions (particularly diabetes mellitus), and localization in the mandibular molar region.

References

Nemcovsky CE, Calvo Guirado JL, Moses O. Periodontal aspects of endodontic–periodontal lesions. Clin Dent Rev. 2019 May 27;3(1):5. DOI: 10.1007/s41894-019-0044-x

Rotstein I, Simon JH. The endo‐perio lesion: a critical appraisal of the disease condition. Endod Topics. 2006 Mar;13(1):34-56. DOI: 10.1111/j.1601-1546.2006.00211.x

Papapanou PN, Sanz M, Buduneli N, Dietrich T, Feres M, Fine DH, Flemmig TF, Garcia R, Giannobile WV, Graziani F, Greenwell H. Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions. J Periodontol. 2018 Jun;89:S173-82. DOI: 10.1002/JPER.17-0721

Jepsen S. New classification of periodontal and peri-implant diseases and conditions. Endod Prac Today. 2020 Jan 1;14(1).

Herrera D, Retamal‐Valdes B, Alonso B, Feres M. Acute periodontal lesions (periodontal abscesses and necrotizing periodontal diseases) and endo‐periodontal lesions. J Clin Periodontol. 2018 Jun;45:S78-94. DOI: 10.1111/jcpe.12941

Sălceanu M, Melian A, Dascălu C, Giuroiu C, Concita C, Topoliceanu C, Melian D, Frumuzache A, Solomon SM, Mârţu MA. Endo-Periodontal Lesions in Endodontically Treated Teeth with Periapical Pathology. Diagnostics. Diagnostics. 2025 Jun 30;15(13):1663. DOI: 10.3390/diagnostics15131663

Ruetters M, Gehrig H, Kronsteiner D, Schuessler DL. Prevalence of endo-perio lesions according to the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Disease in a university hospital. Quintessence Int. 2022 Feb 1;53(2):134-142. DOI: 10.3290/j.qi.b2091245

Elabdeen HR, Berggreen E, Jensen KH, Sulo G, Kvalheim SF, Hasselgren LC, Gerdts E, Iversen MM, Bolstad AI, Bunæs DF. Prevalence of Periodontitis in a 70‐Year‐Old Population in Western Norway According to the ACES 2018 Classification Framework: A Cross‐Sectional Study. J Clin Periodontol. 2025 May;52(5):754-61. DOI: 10.1111/jcpe.14128

Trindade D, Carvalho R, Machado V, Chambrone L, Mendes JJ, Botelho J. Prevalence of periodontitis in dentate people between 2011 and 2020: a systematic review and meta‐analysis of epidemiological studies. J Clin Periodontol. 2023 May;50(5):604-26. DOI: 10.1111/jcpe.13769

Alsharif SB, Bakhashwain K, Felemban O, Alsharif MB. Endo-perio relationship knowledge, understanding, and confidence among dentists. Adv Med Educ Pract. 2023 Dec 31:195-201. DOI: 10.2147/AMEP.S401932

Çırakoğlu YN, Karayürek F. Knowledge and awareness levels of dentists’ about the endo-perio lesions: the questionnaire-based research. Adıyaman Univ Sağlık Bilim Derg. 2021;7(1):64-70. DOI:10.30569.adiyamansaglik.815597

Sari ET, Altındal D. Evaluation of the Prevalence of Endo-Periodontal Lesions According to the New Classification of Periodontal and Peri-Implant Diseases. European J Ther. 2025;31(6):376–388. DOI: 10.58600/eurjther2755

Cucolo FC, Bonvalente MC, Barroso EM, Toledo BE, Camargo GA, Souza AA, Zuza EC. Endo-perio lesions prevalence in non-molar and molar teeth: a pilot study. Rev Odontol UNESP. 2021 Oct 25;50:e20210037. DOI: 10.1590/1807-2577.03721

Robo I, Heta S, Haxhiu E, Qirjazi B, Ostreni V. Endo-perio Lesions—Radiographic Diagnosis of Specific Classifications. SN Compr Clin Med. 2022 Sep 26;4(1):211. https://doi.org/10.1007/s42399-022-01291-1

Dako T, Lazăr AP, Mârṭu MA, Lazăr L. Prevalence of endo-perio lesions among adult patients. an observational study. Rom J Med Dent Educ. 2021 May;10(3):16-21.

Shiggaon LB, Kingaonkar A, Kour T, Bhavsar S, Ayaz M, Chaudhary A, Gupta S, Shiggaon L, Ayaz M. Assessment of Risk Factors and Prognostic Predictors for Endo-Perio Lesions in Indian Cohorts: An Observational Study. Cureus. 2024 Sep 17;16(9). DOI: 10.7759/cureus.69598

Babu A, Saha A, Vairagade SP, Kumar A, Arya A, Tekam DA, Nayak R. Prevalence Rate of Endodontic–Periodontic Lesion in Young versus Adult Patients: A Comparative Analysis. J Pharm Bioallied Sci. 2025 Sep 1;17(Suppl 3):S2599-601. DOI: 10.4103/jpbs.jpbs_848_25

Rajasekar A. Prevalence of endo perio lesion-an institutional study. Int J Dent Oral Sci. 2021:2858-62. DOI: 10.19070/2377-8075-21000580

Altaf A, Jeelani M, Basher A. Assessment of prevalence of Endo-perio lesions among patients of known population: An observational study. prevalence. Int J Appl Dent Sci. 2019;102:14-89.

Güneç HG, Paksoy T, Atalay C, Aydın K. Retrospective evaluation of the prevalence of endodontic-periodontal lesions on panoramic images in the latest classification of periodontal and peri-implant diseases. J Health Sci Med. 2023 Jan 31;6(4):737-44. DOI: 10.32322/jhsm.1293681

Singh R, Singh N, Chauhan S, Siddiqui LT, Bhola L, Sale MS, Meharwade V, Ismail PM, Manas A. Correlation between endo-perio lesions and systemic diseases: A cross-sectional study. Bioinformation. 2025 May 31;21(5):1144. DOI: 10.6026/973206300211144

Abdullah R, Ayoub S. Prevalence of true combined endodontic-periodontal lesions in adult patients with and without diabetes: A cross sectional survey. Int J Appl Dent. Sci. 2023;9:316-319.

Published

2026-05-29

How to Cite

Гончарук-Хомин, М. Ю., Богдан, О. М., Бокоч, А. В., & Баранець, В. В. (2026). Regarding objective assessment of endo-periodontal pathologies prevalence. Scientific Bulletin of the Uzhhorod University. Series «Medicine», (1(73), 82-88. https://doi.org/10.32782/2415-8127.2026.73.14

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