Biochemistry as a fundamental medical discipline and innovative methods of its tеаching

Authors

DOI:

https://doi.org/10.32782/2415-8127.2025.71.13

Keywords:

biochemistry, innovative teaching methods, Krok-1, problem-based learning, interactive teaching methods

Abstract

Introduction. Teaching biochemistry is an important component of the educational process at medical universities. The need for fundamental knowledge of biochemistry for medical students is actively discussed in the scientific literature. Studies show that without deep knowledge of biochemistry, it is impossible to effectively master other medical disciplines. Students’ assimilation of knowledge about biochemical processes in the human body is the basis for understanding the pathogenesis of diseases. Students who have deep knowledge of biochemistry are able to better interpret clinical situations. Physiology, pathology, pharmacology and clinical medicine are closely related to biochemistry, therefore, teaching this discipline should be as effective as possible. Aim. To study the main features and approaches to teaching biochemistry at the medical faculty, to determine the role of innovative teaching methods in the formation of professional competence of future doctors. To analyze which of the academic disciplines included in the Step-1 exam is the most difficult to master and to assess the place of biochemistry in this rating. Materials and methods. Literature review on research on different approaches to teaching biochemistry.Online survey using Google Forms on the characteristics of exam subjects Step-1. Results. One of the important areas is the integration of biochemistry with clinical disciplines, which allows students to better understand the connection between theoretical knowledge and practical medicine. Problem-based learning as one of the interactive methods is an important aspect of modern medical education in Ukraine. Multimedia technologies are also being introduced into the teaching process in Ukraine, which include the use of interactive presentations, video lectures, virtual laboratories, online courses, etc. This approach allows students to better perceive complex material and actively interact with it, and the use of electronic platforms allows students to practice in real time, which increases the effectiveness of learning. The introduction of the latest technologies and methods in teaching biochemistry for medical students is an integral part not only of better learning of the material, but also of successfully passing the Step-1 integrated licensing exam. According to the results of the survey, it was found that the most difficult subjects to study in general are pathological anatomy, pharmacology and biochemistry. The respondents considered biology to be the easiest subject to learn. In general, according to the respondents, such disciplines as physiology, pathological physiology and pharmacology will be most useful in their future professional activities.Conclusions. Teaching biochemistry and preparing medical students for the Step-1 exam are important components of the educational process. Considering the results of the survey, it should be noted that students do not fully understand the importance of mastering this subject for their future professional activities. Due to its complexity, biochemistry requires teachers to use innovative approaches that stimulate critical thinking and contribute to better learning of the material.

References

Gallan AJ, Offner GD, Symes K. Vertical integration of biochemistry and clinical medicine using a near-peer learning model. Biochem Mol Biol Educ. 2016 Nov 12;44(6):507-516. doi: 10.1002/bmb.20972

Osheroff N, Niederhoffer EC, Sabina RL, Cline SD, Wimmer MJ, Franklin DS, Diekman AB, Hogg T, Kearney KR, King SC, Pearson D, Slaughter CA, Thompson K. Teaching Biochemistry to Students of Medicine, Pharmacy & Dentistry: 5th International Conference of the Association of Biochemistry Course Directors (ABCD) Santa Fe, NM, USA, May 3-7, 2015. Med Sci Educ. 2015 Dec;25(4):473-477. doi: 10.1007/s40670-015-0160-4

Kwan CY. Problem-based learning and teaching of medical pharmacology. Naunyn Schmiedebergs Arch Pharmacol. 2002 Jul;366(1):10-7. doi: 10.1007/s00210-002-0561-y

Silva C. Exploring the Role of Clinical Biochemistry in Disease Diagnosis and Management: Current Trends and Future Directions. Annals of Clinical and Laboratory Research. 2023 Feb 27;11(02):1-2. doi: 10.36648/2386-5180.23.11.458

Herman DS, Rhoads DD, Schulz WL, Durant TJS. Artificial Intelligence and Mapping a New Direction in Laboratory Medicine: A Review. Clin Chem. 2021 Nov 1;67(11):1466-1482. doi: 10.1093/clinchem/hvab165

Shulhai AH, Fedoniuk LIa, Mudra AIe, Oleshchuk OM. Mizhdystsyplinarna intehratsiia yak skladova problemno-oriientovanoho navchannia u medychnomu universyteti [Interdisciplinary integration as a component of problem-based learning at a medical university]. Medychna osvita. 2018(4):113-116. [in Ukrainian] doi: 10.11603/me.2414-5998.2018.4.9342

Dolzhkovyi SV, Kryzhanovskyi OA, Ohanezian AH, Sheiko VD. Vykorystannia metodu problemno-oriientovanoho navchannia v roboti zi studentamy-medykamy [Using the problem-based learning method in working with medical students]. Suchasni trendy rozvytku medychnoi osvity: perspektyvy i zdobutky: materialy navch.-nauk. konf. z mizhnar. Uchastiu, m. Poltava 24 bereznia 2022 r. Poltava, 2022:95-96. [in Ukrainian] https://surl.li/tfqnyi

Filippova LV. Komp’iuterni tekhnolohii pid chas vyvchennia biokhimii [Computer technologies in the study of biochemistry]. Aktualni pytannia humanitarnykh nauk. 2021;46(2):179-184. [in Ukrainian] doi: 10.24919/2308-4863/46-2-29

Kharchenko YuV. Orhanizatsiia samostiinoi roboty studentiv pry vyvchenni biokhimii [Organization of independent work of students in the study of biochemistry]. Rozvytok intelektualnykh umin i tvorchykh zdibnostei uchniv ta studentiv u protsesi navchannia dystsyplin pryrodnycho-matematychnoho tsyklu «ITM*plius – 2017»: materialy Mizhnarodnoi dystantsiinoi naukovo-metodychnoi konferentsii (1-2 bereznia 2017 r., m. Sumy). 2017:86-87. [in Ukrainian] https://surl.li/ufpusr

Kuzmina IIu, Kuzmina OO. Metodyka vykorystannia novitnikh tekhnolohii dlia otsiniuvannia roboty studentiv u medychnykh zakladakh vyshchoi osvity [Methodology for using the latest technologies for assessing student performance in medical institutions of higher education]. Innovatsiini tekhnolohii navchannia: dosvid vprovadzhennia ta perspektyvy rozvytku: materialy LIV navchalno-metodychnoi konferentsii KhNMU (Kharkiv, 17 bereznia 2021 r.) / Ministerstvo okhorony zdorovia Ukrainy, Khark. nats. med. un-t. Kharkiv : KhNMU, 2021;11:78-81. [in Ukrainian] https://surl.gd/bfoxpt

Elnashar MM. FastFeedback Questions: A new teaching method. Biochem Mol Biol Educ. 2018 Mar;46(2):121-129. doi: 10.1002/bmb.21103

Abdelazim AM, Gaber DA, Adam KM, El-Ashkar AM, Abdelmalak HW. Use of mobile learning applications as an innovative method for the teaching of biochemistry. Biochem Mol Biol Educ. 2023 Nov-Dec;51(6):627-634. doi: 10.1002/bmb.21774

Kadavakollu S, Kumar R, Aradhyula L, White S, Lamichhane-Khadka R, Merino E, Boyanovsky B. Ten practical tips for integration of biochemistry topics into systems-based medical school curriculum. MedEdPublish. 2023 Apr 14;13(23):23. doi: 10.12688/mep.19633.1

Sun L, Liu D, Lian J, Yang M. Application of flipped classroom combined with virtual simulation platform in clinical biochemistry practical course. BMC Med Educ. 2023 Oct 16;23(1):771. doi: 10.1186/s12909-023-04735-x

Zhao YM, Liu SS, Wang J. Application of data-driven blended online-offline teaching in medicinal chemistry for pharmacy students: a randomized comparison. BMC Med Educ. 2024 Jul 9;24(1):738. doi: 10.1186/s12909-024-05701-x

Published

2025-04-30

How to Cite

Ростока, Л. М., Бурмістрова, Я. Ю., & Сіткар, А. Д. (2025). Biochemistry as a fundamental medical discipline and innovative methods of its tеаching. Scientific Bulletin of the Uzhhorod University. Series «Medicine», (1(71), 81-85. https://doi.org/10.32782/2415-8127.2025.71.13